Aspects from the biomedical gerontology

Edmonton: a future center for pioneering biomedical gerontology?

Biomedical aspects of lectins.

Studies on lectins are having an increasing impact on medicine, by providing new tools for diagnosis, helping to solve clinical problems, and giving new insights into pathological processes (Lis & Sharon, 1986a, b; Sharon & Lis, 1988). Two early discoveries: that certain lectins are bloodgroup specific while others are mitogenic, have led to their widespread use for blood typing, for assessing ...

Biomedical aspects of chiral molecules

This article defines some of the terms used in chiral chemistry and some of the basic mechanistic issues that arise in stereochemistry in pharmacology. Attention is also drawn to the impact of stereochemistry on drug regulation and its significance for new drug development. The stereoselectivity of drugs is underpinned by the fact that the human body is essentially a chiral structure. The ratio...

When will the biology of aging become useful? Future landmarks in biomedical gerontology.

Where should we look to find the causes of and cure for aging? This essay considers a number of scientific discoveries, not yet made, that might dramatically increase the proportion of biogerontologists doing useful work. I will consider, in turn, problems and prospects in the areas of comparative biology, mammalian and invertebrate genetics, biomarker research, caloric restriction, and clonal ...

Molecular gerontology: from homeodynamics to hormesis.

The science and study of the biological basis of aging, biogerontology, is now a well-established field with solid scientific base. A paradigm-shift in gerontology has occurred by realising the fact that biological aging occurs in spite of the presence of complex homeodynamic pathways of maintenance, repair and defence, and there is no "enemy within". This viewpoint separates the modulation of ...